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1982 - 1985年对加利福尼亚州农药施用者尿液中的杀虫脒及其代谢物残留进行监测。

Monitoring the urine of pesticide applicators in California for residues of chlordimeform and its metabolites 1982-1985.

作者信息

Maddy K T, Knaak J B, Gibbons D B

出版信息

Toxicol Lett. 1986 Oct;33(1-3):37-44. doi: 10.1016/0378-4274(86)90069-x.

DOI:10.1016/0378-4274(86)90069-x
PMID:3775820
Abstract

Chlordimeform (Cdf) is readily absorbed through the skin of pesticide applicators. It also enters the body when breathed into the lungs. Cdf can be found in the urine of workers who handle or are involved in applying pesticide products which contain the chemical, even when they are wearing special protective clothing and respirators. Because of the adverse health effects seen in heavily exposed workers and the cancerous tumors seen in mice, special precautions are necessary when handling products containing Cdf to reduce the risk of adverse health effects. Because Cdf is known to enter the body very easily, with serious injury potential, workers handling pesticide products containing Cdf in California are required to have medical supervision including a blood test at the beginning and end of each application season and monthly testing of urine for possible cellular change and pesticide residues during the time Cdf exposure takes place. This program is designed to keep worker exposure as low as possible.

摘要

杀虫脒(Cdf)很容易通过农药施用者的皮肤被吸收。当被吸入肺部时,它也会进入人体。即使在处理或参与施用含有该化学物质的农药产品的工人穿着特殊防护服和佩戴呼吸器的情况下,在他们的尿液中也能检测到Cdf。由于在高暴露工人身上观察到了不良健康影响,并且在小鼠身上发现了癌性肿瘤,因此在处理含有Cdf的产品时必须采取特殊预防措施,以降低不良健康影响的风险。由于已知Cdf很容易进入人体,且具有严重的潜在伤害,在加利福尼亚州,处理含有Cdf的农药产品的工人必须接受医疗监督,包括在每个施用季节开始和结束时进行血液检测,以及在Cdf暴露期间每月检测尿液,以检测可能的细胞变化和农药残留。该计划旨在将工人的暴露水平保持在尽可能低的水平。

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