[强直性脊柱炎中的人类白细胞抗原DRw]
[HLA DRw in ankylosing spondylitis].
作者信息
Gaucher A, Raffoux C, Netter P, Faure G, Pourel J, Streiff F
出版信息
Rev Rhum Mal Osteoartic. 1978 May;45(5):335-8.
PMID:307806
Abstract
The association of ankylosing spondylarthritis with the B locus and more specifically with the B 27 antigen, is the closet known for any illness. The absence of linkage with the DRw antigens studied during this project, in 50 patients, can give rise to the hypothesis that spondylarthritis is associated with determinants situated on the B lymphocytes, linked to the HLA-B locus.
摘要
强直性脊柱炎与B位点，更具体地说是与B27抗原的关联，是所有疾病中已知关联最为紧密的。在本项目中对50名患者进行研究，结果显示强直性脊柱炎与DRw抗原无连锁关系，由此可提出假说：脊柱关节炎与位于B淋巴细胞上、与HLA - B位点连锁的决定簇相关。
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