Perrillo R P, Pohl D A, Roodman S T, Tsai C C
JAMA. 1981 Feb 6;245(5):494-6.
We treated a patient in whom acute non-A, non-B hepatitis was complicated by a serum sickness-like syndrome (rash, arthralgias). Serum from this patient demonstrated a fall in C3, C4, and total hemolytic complement levels during the syndrome, in association with circulating IgM immune complexes. Fatal aplastic anemia developed later in the patient. This case illustrates that non-A, non-B hepatitis may be complicated by immune complex features that have previously been emphasized to occur with acute hepatitis B. Additional evidence supporting the occurrence of this clinical picture in non-B forms off viral hepatitis is presented.
我们治疗了一位急性非甲非乙型肝炎并发血清病样综合征（皮疹、关节痛）的患者。该患者的血清在综合征期间显示C3、C4和总溶血补体水平下降，并伴有循环IgM免疫复合物。患者后来发展为致命的再生障碍性贫血。该病例表明，非甲非乙型肝炎可能并发免疫复合物特征，而这些特征以前曾被强调为急性乙型肝炎所具有。本文还提供了支持这种临床情况在非乙型病毒性肝炎中出现的更多证据。
