Krrok G, Waldenström J G
Acta Med Scand. 1978;203(4):289-92. doi: 10.1111/j.0954-6820.1978.tb14875.x.
We report the history of a patient, who had recurrent patches of erythema on the trunk and extremities for some years. The diagnosis of erythema elevatum diutinum or annulare centrifugum was discussed. The patient developed a monoclonal IgA lambda fraction and clinical signs of myeloma. Treatment with cyclophosphamide stopped the development of erythema and also caused the M-component to disappear. This improvement has persisted even without cytostatic treatment. Another patient with prostatic carcinoma and relapsing annular erythema was cured of his skin lesions, when his carcinoma was treated with estrogens. The literature is reviewed.
我们报告了一名患者的病史，该患者躯干和四肢反复出现红斑数年。讨论了持久性隆起性红斑或离心性环状红斑的诊断。该患者出现了单克隆IgA λ组分及骨髓瘤的临床体征。环磷酰胺治疗使红斑停止发展，同时也使M蛋白成分消失。即使在未进行细胞抑制治疗的情况下，这种改善也一直持续。另一名患有前列腺癌和复发性环状红斑的患者，在其前列腺癌接受雌激素治疗后，皮肤病变得到治愈。本文对相关文献进行了综述。
