Romanenko A V
Ukr Biokhim Zh (1978). 1980 Sep-Oct;52(5):624-7.
The membrane potential, inhibition postsynaptic potentials, resistance of the guinea pig taenia coli membrane were studied as affected by exogenic vitamin PP and its derivatives of nucleotide nature. It is shown that nicotinic acid, nicotinamide, NAD+, NADH, NADP+, NADPH evoke the membrane hyperpolarization and a decrease in the amplitude of the inhibition postsynaptic potentials. Nicotinamid dinucleotides cause a decrease in the membrane resistance, whereas nicotinic acid and nicotinamide do not affect this parameter. The character of the observed effects does not depend on the degree of nicotinamide dinucleotides oxidation.
研究了外源性维生素PP及其核苷酸性质的衍生物对豚鼠结肠带膜电位、抑制性突触后电位和膜电阻的影响。结果表明，烟酸、烟酰胺、NAD+、NADH、NADP+、NADPH可引起膜超极化，并使抑制性突触后电位的幅度降低。烟酰胺二核苷酸可导致膜电阻降低，而烟酸和烟酰胺不影响该参数。观察到的效应特征不依赖于烟酰胺二核苷酸的氧化程度。
