吸入性α受体阻滞剂对哮喘气流阻塞的影响。
Effect of inhaled alpha-blocker on airflow obstruction in asthma.
作者信息
Britton J, Ayres J, Cochrane G M
出版信息
J R Soc Med. 1981 Sep;74(9):646-8. doi: 10.1177/014107688107400904.
Abstract
A controlled study of the effect on airflow obstruction of 30 mg of the alpha-blocker thymoxamine given by inhalation is reported in 10 patients with chronic stable asthma. No significant change in peak expiratory flow rate was seen with either thymoxamine or placebo in any patient. Alpha-adrenergic receptors are therefore unlikely to contribute significantly to resting bronchomotor tone in chronic stable asthma.
摘要
据报道，对10例慢性稳定型哮喘患者进行了一项对照研究，观察吸入30毫克α受体阻滞剂百里胺对气流阻塞的影响。在任何患者中，百里胺或安慰剂组的呼气峰值流速均未出现显著变化。因此，α肾上腺素能受体不太可能对慢性稳定型哮喘患者静息时的支气管运动张力产生显著影响。
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本文引用的文献
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