含拉氧头孢血清中妥布霉素的测定方法
Procedure for assay of tobramycin in serum containing moxalactam.
作者信息
Mahoney D F, Butler T F, Turner J R
出版信息
Antimicrob Agents Chemother. 1981 May;19(5):934-6. doi: 10.1128/AAC.19.5.934.
Abstract
Moxalactam was examined as a substrate for 11 beta-lactamases. Hydrolysis was shown only with the beta-lactamase from Bacillus cereus, a nonpathogenic bacterium. Tobramycin was assayed in tobramycin-moxalactam mixtures by using this beta-lactamase.
摘要
对羟羧氧酰胺菌素作为11种β-内酰胺酶的底物进行了研究。结果表明，只有蜡样芽孢杆菌（一种非致病性细菌）产生的β-内酰胺酶能使其水解。利用这种β-内酰胺酶对妥布霉素-羟羧氧酰胺菌素混合物中的妥布霉素进行了测定。
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