仓鼠棕色脂肪组织线粒体成分对冷适应的变化。
Changes in mitochondrial components of hamster brown adipose tissue in response to cold acclimation.
作者信息
Yacoe M E
出版信息
Biochem J. 1981 Feb 15;194(2):653-6. doi: 10.1042/bj1940653.
Abstract
Cold acclimation of hamsters was found to result in an increase in cytochrome concentration relative to ATPase activity in brown adipose tissue mitochondria, but not in liver mitochondria. These data lend support to the hypothesis that the uncoupled respiration characteristic of non-shivering thermogenesis is the result of an adaptive change in the composition of brown adipose tissue mitochondria in response to cold acclimation.
摘要
研究发现，仓鼠经冷驯化后，棕色脂肪组织线粒体中的细胞色素浓度相对于ATP酶活性有所增加，但肝脏线粒体中并非如此。这些数据支持了以下假说：非颤抖性产热解偶联呼吸的特征是棕色脂肪组织线粒体组成因冷驯化而发生适应性变化的结果。
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本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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2
Comparable and specific proportions in the mitochondrial enzyme activity pattern.线粒体酶活性模式中的可比和特定比例。
Biochem Biophys Res Commun. 1962 Jun 4;7:425-9. doi: 10.1016/0006-291x(62)90328-5.
3
Proportions of mitochondrial enzymes and pyridine nucleotides.线粒体酶和吡啶核苷酸的比例
Biochem Biophys Res Commun. 1962 Jun 4;7:430-2. doi: 10.1016/0006-291x(62)90329-7.
4
A METHOD FOR THE SIMULTANEOUS QUANTITATIVE ESTIMATION OF CYTOCHROMES A, B, C1, AND C IN MITOCHONDRIA.一种同时定量测定线粒体中 CytA、CytB、CytC1 和 CytC 的方法。
Arch Biochem Biophys. 1964 Sep;107:537-43. doi: 10.1016/0003-9861(64)90313-3.
5
Studies of the mitochondrial energy-transfer system of brown adipose tissue.棕色脂肪组织线粒体能量转移系统的研究。
J Cell Biol. 1967 Jul;34(1):293-310. doi: 10.1083/jcb.34.1.293.
6
Metabolite transport in mitochondria: an example for intracellular membrane function.线粒体中的代谢物运输：细胞内膜功能的一个实例
Essays Biochem. 1970;6:119-59.
7
Mitochondrial citric acid cycle and related enzymes: adaptive response to exercise.线粒体柠檬酸循环及相关酶：对运动的适应性反应
Biochem Biophys Res Commun. 1970 Sep 30;40(6):1368-73. doi: 10.1016/0006-291x(70)90017-3.
8
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9
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Eur J Biochem. 1970 Oct;16(2):313-35. doi: 10.1111/j.1432-1033.1970.tb01086.x.
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