影响头孢哌酮对脆弱拟杆菌群体外活性的因素。
Factors affecting the in vitro activity of cefoperazone against the Bacteroides fragilis group.
作者信息
Sutter V L, Kwok Y Y
出版信息
Antimicrob Agents Chemother. 1981 Dec;20(6):723-5. doi: 10.1128/AAC.20.6.723.
Abstract
The in vitro activity of cefoperazone against 32 strains of bacteria of the Bacteroides fragilis group was determined on four media by using a variety of test parameters. Lower mean minimal inhibitory concentrations (MICs) were obtained on Mueller-Hinton blood agar and supplemented brain heart infusion agar than were obtained on brucella laked blood agar or Wilkins-Chalgren agar. Higher MICs were obtained with 6-h inocula than with 24-h inocula, and slightly higher MICs were obtained with tests read at 48 as compared with 24 h. Conducting tests in an anaerobic glove box had little effect. The greatest differences in mean MICs were seen with inoculum densities of 10(4) and 10(5) colony-forming units.
摘要
采用多种测试参数，在四种培养基上测定了头孢哌酮对32株脆弱拟杆菌属细菌的体外活性。与布鲁氏菌溶血琼脂或威尔金斯-查尔格伦琼脂相比，在穆勒-欣顿血琼脂和补充脑心浸液琼脂上获得的平均最低抑菌浓度（MIC）更低。接种6小时时获得的MIC高于接种24小时时，且与24小时读数的测试相比，48小时读数的测试获得的MIC略高。在厌氧手套箱中进行测试影响不大。接种密度为10⁴和10⁵菌落形成单位时，平均MIC的差异最大。
相似文献
1
Factors affecting the in vitro activity of cefoperazone against the Bacteroides fragilis group.
Antimicrob Agents Chemother. 1981 Dec;20(6):723-5. doi: 10.1128/AAC.20.6.723.
2
Effect of inoculum size and medium on activity of seven antimicrobial agents against Bacteroides fragilis strains.
Clin Ther. 1989 Nov-Dec;11(6):828-33.
3
Comparative in vitro activity of 1-oxa-beta-lactam (LY127935) and cefoperazone with other beta-lactam antibiotics against anaerobic bacteria.
Antimicrob Agents Chemother. 1980 Feb;17(2):129-31. doi: 10.1128/AAC.17.2.129.
4
Effect of beta-lactamase inhibitors on the antimicrobial activity of cefoperazone, cefotaxime, and ceftizoxime against aerobic and anaerobic beta-lactamase producing bacteria.
Diagn Microbiol Infect Dis. 1987 Sep;8(1):61-5. doi: 10.1016/0732-8893(87)90049-6.
5
Effect of inoculum, pH, and medium on the activity of ciprofloxacin against anaerobic bacteria.
Antimicrob Agents Chemother. 1984 Mar;25(3):342-3. doi: 10.1128/AAC.25.3.342.
6
Activity of sulfamethoxazole and trimethoprim against Bacteroides fragilis.
Antimicrob Agents Chemother. 1976 May;9(5):736-40. doi: 10.1128/AAC.9.5.736.
7
Establishment of minimum inhibitory concentrations of cefoperazone for control and reference anaerobic organisms.
J Clin Microbiol. 1983 Apr;17(4):711-4. doi: 10.1128/jcm.17.4.711-714.1983.
8
Development of EUCAST disk diffusion method for susceptibility testing of the Bacteroides fragilis group isolates.
Anaerobe. 2015 Feb;31:65-71. doi: 10.1016/j.anaerobe.2014.10.008. Epub 2014 Nov 11.
9
[Comparative effect of apalcillin and other beta-lactam antibiotics against the Bacteroides fragilis group].
Pathol Biol (Paris). 1989 Jun;37(5 Pt 2):523-7.
10
Cefoperazone (T-1551), a new semisynthetic cephalosporin: comparison with cephalothin and gentamicin.
Antimicrob Agents Chemother. 1980 Apr;17(4):743-9. doi: 10.1128/AAC.17.4.743.
引用本文的文献
1
Differences in susceptibilities of species of the Bacteroides fragilis group to several beta-lactam antibiotics: indole production as an indicator of resistance.
Antimicrob Agents Chemother. 1982 Oct;22(4):628-34. doi: 10.1128/AAC.22.4.628.
本文引用的文献
1
Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporin.
Antimicrob Agents Chemother. 1980 Apr;17(4):583-90. doi: 10.1128/AAC.17.4.583.
2
Susceptibilities of anaerobic bacteria to cefoperazone and other antibiotics.
Antimicrob Agents Chemother. 1980 Jun;17(6):957-60. doi: 10.1128/AAC.17.6.957.
3
Cefoperazone (T-1551), a new semisynthetic cephalosporin: comparison with cephalothin and gentamicin.
Antimicrob Agents Chemother. 1980 Apr;17(4):743-9. doi: 10.1128/AAC.17.4.743.
4
Susceptibility of anaerobic bacteria to cefoperazone and other beta-lactam antibiotics.
Clin Ther. 1980;3(Spec Issue):34-8.
5
Influence of inoculum size on activity of cefoperazone, cefotaxime, moxalactam, piperacillin, and N-formimidoyl thienamycin (MK0787) against Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 1980 Dec;18(6):893-6. doi: 10.1128/AAC.18.6.893.
6
Comparative in vitro activity of 1-oxa-beta-lactam (LY127935) and cefoperazone with other beta-lactam antibiotics against anaerobic bacteria.
Antimicrob Agents Chemother. 1980 Feb;17(2):129-31. doi: 10.1128/AAC.17.2.129.
7
In vitro activity of N-formimidoyl thienamycin, moxalactam, and other new beta-lactam agents against Bacteroides fragilis: contribution of beta-lactamase to resistance.
Antimicrob Agents Chemother. 1981 Feb;19(2):248-52. doi: 10.1128/AAC.19.2.248.
8
Susceptibility of anaerobes to cefoxitin and other cephalosporins.
Antimicrob Agents Chemother. 1975 Feb;7(2):128-32. doi: 10.1128/AAC.7.2.128.
9
In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin.
Antimicrob Agents Chemother. 1979 Dec;16(6):731-5. doi: 10.1128/AAC.16.6.731.
10
Comparative activity and beta-lactamase stability of cefoperazone, a piperazine cephalosporin.
Antimicrob Agents Chemother. 1979 Aug;16(2):150-7. doi: 10.1128/AAC.16.2.150.
Zotero 插件