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Rapid hydrolysis of deoxynucleoside triphosphates accompanies DNA synthesis by T4 DNA polymerase and T4 accessory proteins 44/62 and 45.

作者信息

Roth A C, Nossal N G, Englund P T

出版信息

J Biol Chem. 1982 Feb 10;257(3):1267-73.

PMID:6460024
Abstract
摘要

相似文献

1
Rapid hydrolysis of deoxynucleoside triphosphates accompanies DNA synthesis by T4 DNA polymerase and T4 accessory proteins 44/62 and 45.脱氧核苷三磷酸的快速水解伴随着T4 DNA聚合酶以及T4辅助蛋白44/62和45进行的DNA合成。
J Biol Chem. 1982 Feb 10;257(3):1267-73.
2
Effects of altered nucleotide concentrations on the fidelity of DNA replication.核苷酸浓度改变对DNA复制保真度的影响。
Basic Life Sci. 1985;31:117-26. doi: 10.1007/978-1-4613-2449-2_7.
3
Persistence of DNA synthesis arrest sites in the presence of T4 DNA polymerase and T4 gene 32, 44, 45 and 62 DNA polymerase accessory proteins.在存在T4 DNA聚合酶以及T4基因32、44、45和62 DNA聚合酶辅助蛋白的情况下，DNA合成停滞位点的持续性。
Nucleic Acids Res. 1986 Apr 25;14(8):3343-62. doi: 10.1093/nar/14.8.3343.
4
Bacteriophage T4 gene 44/62 and gene 45 polymerase accessory proteins stimulate hydrolysis of duplex DNA by T4 DNA polymerase.
J Biol Chem. 1982 Oct 25;257(20):12435-43.
5
The 3'-5' proofreading exonuclease of bacteriophage T4 DNA polymerase is stimulated by other T4 DNA replication proteins.噬菌体T4 DNA聚合酶的3'-5'校对核酸外切酶受到其他T4 DNA复制蛋白的刺激。
J Biol Chem. 1983 Aug 25;258(16):9649-56.
6
Structure and function of the bacteriophage T4 DNA polymerase holoenzyme.
Biochemistry. 1992 Sep 22;31(37):8675-90. doi: 10.1021/bi00152a001.
7
Bacteriophage T4 DNA primase-helicase. Characterization of the DNA synthesis primed by T4 61 protein in the absence of T4 41 protein.噬菌体T4 DNA引发酶-解旋酶。在缺乏T4 41蛋白的情况下由T4 61蛋白引发的DNA合成的特性。
J Biol Chem. 1987 Aug 5;262(22):10879-85.
8
The bacteriophage T4 DNA replication fork. Only DNA helicase is required for leading strand DNA synthesis by the DNA polymerase holoenzyme.噬菌体T4 DNA复制叉。DNA聚合酶全酶进行前导链DNA合成仅需DNA解旋酶。
J Biol Chem. 1989 Jul 25;264(21):12220-5.
9
Fidelity of DNA replication catalysed in vitro on a natural DNA template by the T4 bacteriophage multi-enzyme complex.T4噬菌体多酶复合物在天然DNA模板上体外催化DNA复制的保真度。
Nature. 1980 May 29;285(5763):300-5. doi: 10.1038/285300a0.
10
Two types of replication proteins increase the rate at which T4 DNA polymerase traverses the helical regions in a single-stranded DNA template.两种复制蛋白提高了T4 DNA聚合酶在单链DNA模板中穿越螺旋区域的速率。
J Biol Chem. 1981 Apr 25;256(8):4087-94.

引用本文的文献

1
Mechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activity.具有降低的核酸外切酶活性的耐药病毒聚合酶突变体揭示了更昔洛韦诱导链终止的机制。
Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17462-7. doi: 10.1073/pnas.1405981111. Epub 2014 Nov 24.
2
Engineering processive DNA polymerases with maximum benefit at minimum cost.以最小成本获得最大效益的工程化连续 DNA 聚合酶。
Front Microbiol. 2014 Aug 4;5:380. doi: 10.3389/fmicb.2014.00380. eCollection 2014.
3
Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication.
DNA聚合酶δ闲置时在滞后链DNA复制过程中维持可连接的切口。
Genes Dev. 2004 Nov 15;18(22):2764-73. doi: 10.1101/gad.1252304. Epub 2004 Nov 1.
4
Focused genetic recombination of bacteriophage t4 initiated by double-strand breaks.由双链断裂引发的噬菌体T4的定向基因重组。
Genetics. 2002 Oct;162(2):543-56. doi: 10.1093/genetics/162.2.543.
5
Marker-dependent recombination in T4 bacteriophage. IV. Recombinational effects of antimutator T4 DNA polymerase.T4噬菌体中依赖标记的重组。IV. 抗突变T4 DNA聚合酶的重组效应。
Genetics. 1995 May;140(1):13-25. doi: 10.1093/genetics/140.1.13.
6
Yeast 2-microns plasmid DNA replication in vitro: purification of the CDC8 gene product by complementation assay.酵母2微米质粒DNA的体外复制：通过互补测定法纯化CDC8基因产物。
Proc Natl Acad Sci U S A. 1983 Feb;80(3):673-7. doi: 10.1073/pnas.80.3.673.
7
Persistence of DNA synthesis arrest sites in the presence of T4 DNA polymerase and T4 gene 32, 44, 45 and 62 DNA polymerase accessory proteins.在存在T4 DNA聚合酶以及T4基因32、44、45和62 DNA聚合酶辅助蛋白的情况下，DNA合成停滞位点的持续性。
Nucleic Acids Res. 1986 Apr 25;14(8):3343-62. doi: 10.1093/nar/14.8.3343.
8
DNA synthesis arrest sites at the right terminus of rat long interspersed repeated (LINE or L1Rn) DNA family members.大鼠长散在重复（LINE或L1Rn）DNA家族成员右末端的DNA合成停滞位点。
Nucleic Acids Res. 1987 Apr 10;15(7):3155-75. doi: 10.1093/nar/15.7.3155.
9
Ordered deletions for DNA sequencing and in vitro mutagenesis by polymerase extension and exonuclease III gapping of circular templates.通过聚合酶延伸和环状模板的核酸外切酶III缺口进行DNA测序和体外诱变的有序缺失。
Nucleic Acids Res. 1990 May 25;18(10):2961-6. doi: 10.1093/nar/18.10.2961.