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酒精化大鼠输卵管和子宫腔液中乙醇的存在情况。

The presence of ethanol in the oviductal and uterine luminal fluids of alcoholized rats.

作者信息

Sandor S, Gârban Z, Checiu M, Daradics L

出版信息

Morphol Embryol (Bucur). 1981 Oct-Dec;27(4):303-9.

PMID:6460170
Abstract

Blood ethanol level and the presence of ethanol in the oviductal and uterine luminal fluids were determined in female albino rats (Wistar strain) following chronic alcoholization by 20% ethanol offered ad libitum in drinking water during a period of 40-50 and 90-100 days, respectively. Ethanol was found both in the oviductal and in the uterine luminal fluids in lower concentrations as compared with the blood ethanol level. The findings presented suggest the possible direct noxious action of ethanol upon preimplantation development (effects detected in previous investigations). Problems raised by present results are discussed.

摘要

分别在40 - 50天和90 - 100天的时间段内,让雌性白化大鼠(Wistar品系)自由饮用含20%乙醇的饮用水进行慢性酒精化处理后,测定其血液乙醇水平以及输卵管和子宫腔液中乙醇的存在情况。与血液乙醇水平相比,在输卵管和子宫腔液中均发现乙醇浓度较低。所呈现的研究结果表明乙醇可能对植入前发育具有直接有害作用(先前研究中已检测到相关影响)。本文讨论了当前结果所引发的问题。

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