Baadsgaard O, Geisler C, Plesner T, Thestrup-Pedersen K
Arch Dermatol Res. 1985;277(4):304-6. doi: 10.1007/BF00509085.
Four patients with severe contact dermatitis resulting from compositae oleoresin were found to have increased sensitivity to ultraviolet light. All showed a clear reduction of Leu-3a-positive lymphocytes (T helper/inducer cells) and cells expressing the Ia phenotype in their blood. The numbers of T suppressor/cytotoxic (Leu 2a) lymphocytes, monocytes and B lymphocytes were within the normal range. Treatment with azathioprine (150 mg daily) improved the eczema. The number of Leu-3a-positive lymphocytes normalized during therapy, but the number of Ia-positive cells did not.
发现4例因菊科植物含油树脂导致严重接触性皮炎的患者对紫外线的敏感性增加。所有患者血液中Leu - 3a阳性淋巴细胞（T辅助/诱导细胞）和表达Ia表型的细胞均明显减少。T抑制/细胞毒性（Leu 2a）淋巴细胞、单核细胞和B淋巴细胞数量在正常范围内。用硫唑嘌呤（每日150毫克）治疗可改善湿疹。治疗期间Leu - 3a阳性淋巴细胞数量恢复正常，但Ia阳性细胞数量未恢复正常。
