Beta decay and the origin of biological chirality: new experimental results.

The proposed connection between the parity-violating handedness of beta particles in radioactive decay and the sign (L) of biological chirality (the Vester-Ulbricht [V-U] hypothesis) is being investigated by measuring the theoretically predicted asymmetry in the formation of triplet positronium in amino acid enantiomers by low energy positrons under reversal of the helicity of the positrons. We find the asymmetry in leucine to be (0.8 +/- 1.0) X 10(-4), i.e. consistent with the theoretical prediction of 10(-6) to 10(-7). The apparatus is now sensitive enough to test the predicted asymmetry in optically active molecules which have heavy atoms at their chiral centers. The connection between these results and asymmetry in radiolysis by beta-decay electrons is made, and the implications of our limits for the V-U hypothesis discussed. Although the above limits are 10(6) times lower than direct measurements of radiolysis, they are still not small enough to allow us to rule out the V-U hypothesis.