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[有无干扰性蛋白质物质存在时各种消毒剂的杀菌活性]

[Bactericidal activity of various disinfectants with or without interfering protein substances].

作者信息

Chantefort A, Druilles J

出版信息

Pathol Biol (Paris). 1984 Jun;32(5 Pt 2):615-8.

PMID:6462755
Abstract

Determination of bactericidal activity of 15 disinfectants by AFNOR standard NF T 72-151 (in distilled water) and AFNOR standard NF T 72-171 (in the presence of protein) provides practical guidelines for optimal use of the different available products. Inhibition by dirt is weak for products composed chiefly of phenol derivatives, while it is very strong for quaternary ammonium compounds as well as chlorine which therefore require prior cleansing of surfaces to be disinfected. Two strains (out of the five indicated by AFNOR standards), i.e. P. aeruginosa and M. smegmatis, are especially resistant when residual organic material is present. According to specific conditions of use, such as whether surfaces are clean or dirty, or whether a hospital or food factory is involved, appropriate AFNOR standards must be chosen to study the activity of disinfectants in various settings and on different strains.

摘要

按照法国标准化协会标准NF T 72 - 151(在蒸馏水中)和法国标准化协会标准NF T 72 - 171(在有蛋白质存在的情况下)对15种消毒剂的杀菌活性进行测定,可为合理使用不同的现有产品提供实用指南。对于主要由酚类衍生物组成的产品,污垢的抑制作用较弱,而对于季铵化合物以及氯来说,污垢的抑制作用非常强,因此需要对要消毒的表面进行预先清洁。当存在残留有机物质时,两种菌株(法国标准化协会标准指定的五种菌株中的两种),即铜绿假单胞菌和耻垢分枝杆菌,具有特别强的抵抗力。根据具体使用条件,如表面是清洁还是肮脏,或涉及医院还是食品厂,必须选择合适的法国标准化协会标准,以研究消毒剂在各种环境和不同菌株上的活性。

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