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一种测定乙酰水杨酸铝中水杨酸的简易荧光法。

A simple fluorometric method for the determination of salicylic acid in aluminium acetylsalicylate.

作者信息

Wahbi A M, Barary M H, Korany M A

出版信息

Pharm Weekbl Sci. 1984 Jun 22;6(3):118-20. doi: 10.1007/BF01963002.

DOI:10.1007/BF01963002
PMID:6462879
Abstract

A simple, rapid fluorometric method for the determination of salicylic acid in aluminium acetylsalicylate is presented. The method is based on the dissolution of aluminium acetylsalicylate in sodium fluoride-hydrochloric acid solution, filtration and dilution with buffer solution pH = 4 followed by the fluorometric determination of the liberated salicylic acid. The method was applied successfully to the determination of salicylic acid in aluminium acetylsalicylate tablets.

摘要

本文提出了一种简单、快速的荧光分析法,用于测定乙酰水杨酸铝中的水杨酸。该方法基于乙酰水杨酸铝在氟化钠-盐酸溶液中的溶解,过滤并用pH = 4的缓冲溶液稀释,然后荧光法测定释放出的水杨酸。该方法已成功应用于乙酰水杨酸铝片剂中水杨酸的测定。

相似文献

1
A simple fluorometric method for the determination of salicylic acid in aluminium acetylsalicylate.一种测定乙酰水杨酸铝中水杨酸的简易荧光法。
Pharm Weekbl Sci. 1984 Jun 22;6(3):118-20. doi: 10.1007/BF01963002.
2
Determination of aspirin and salicylic acid in aspirin tablets by second derivative ultraviolet spectrometry.用二阶导数紫外光谱法测定阿司匹林片中阿司匹林和水杨酸的含量。
Chem Pharm Bull (Tokyo). 1984 Apr;32(4):1484-90. doi: 10.1248/cpb.32.1484.
3
Determination of related compounds in aspirin by liquid chromatography.用液相色谱法测定阿司匹林中的有关物质。
J Pharm Sci. 1982 May;71(5):511-4. doi: 10.1002/jps.2600710508.
4
Simultaneous determination of aspirin and salicylic acid in bulk aspirin and in plain, buffered, and enteric-coated tablets by high-pressure liquid chromatography with UV and fluorescence detectors.采用配备紫外和荧光检测器的高压液相色谱法同时测定原料药阿司匹林以及普通片剂、缓冲片剂和肠溶衣片中的阿司匹林和水杨酸。
J Pharm Sci. 1980 Oct;69(10):1188-91. doi: 10.1002/jps.2600691018.
5
Fluorometric determination of salicylic acid in buffered aspirin products.缓冲阿司匹林产品中水杨酸的荧光测定法。
J Pharm Sci. 1971 Jan;60(1):114-6. doi: 10.1002/jps.2600600123.
6
Determination of salicylic acid and aspirin in multicomponent tablets by liquid chromatography on a nonionic resin.非离子树脂柱液相色谱法测定复方片剂中的水杨酸和阿司匹林
J Pharm Sci. 1978 Aug;67(8):1066-9. doi: 10.1002/jps.2600670811.
7
Fluorometric determination of salicylic acid in aspirin products including noninterfering, interfering, and buffered substances.荧光法测定阿司匹林产品中水杨酸的含量,包括无干扰、有干扰和缓冲物质。
J Pharm Sci. 1970 Mar;59(3):397-400. doi: 10.1002/jps.2600590328.
8
Aspirin--a national survey V: Determination of aspirin and impurities in enteric coated tablets and suppository formulations and in vitro dissolution of enteric coated tablets.阿司匹林——一项全国性调查V:肠溶衣片和栓剂制剂中阿司匹林及杂质的测定以及肠溶衣片的体外溶出度
J Pharm Sci. 1982 Sep;71(9):1049-52. doi: 10.1002/jps.2600710923.
9
Simultaneous determination of acetylsalicylic and salicylic acids in human serum and aspirin formulations by second-derivative synchronous fluorescence spectrometry.
Analyst. 1991 Apr;116(4):373-8. doi: 10.1039/an9911600373.
10
Comparison of assay methods by second-derivative spectroscopy, colorimetry and fluorescence spectroscopy of salicylic acid in aspirin preparations with a high-performance liquid chromatographic method.用二阶导数光谱法、比色法和荧光光谱法对阿司匹林制剂中的水杨酸进行分析,并与高效液相色谱法进行比较。
J Pharm Biomed Anal. 1994 Mar;12(3):383-7. doi: 10.1016/0731-7085(94)90015-9.

本文引用的文献

1
Aspirin--a national survey II: Determination of salicylic acid in bulk aspirin and aspirin formulations by high-pressure liquid chromatography using a fluorescence detector.阿司匹林——一项全国性调查II:使用荧光检测器通过高压液相色谱法测定原料药阿司匹林及阿司匹林制剂中的水杨酸。
J Pharm Sci. 1980 May;69(5):548-50. doi: 10.1002/jps.2600690518.
2
Aspirin--a national survey I: Semiautomated determination of aspirin in bulk and tablet formulations and salicyclic acid in tablet formulations.
J Pharm Sci. 1980 May;69(5):544-8. doi: 10.1002/jps.2600690517.
3
Rapid high-performance thin-layer chromatography of salicylic acid, salicylamide, ethoxybenzamide and paracetamol in saliva.
J Chromatogr. 1981 May 8;223(2):479-83. doi: 10.1016/s0378-4347(00)80126-7.
4
Determination of salicylic acid in aspirin powder by second derivative ultraviolet spectrometry.用二阶导数紫外光谱法测定阿司匹林粉末中的水杨酸。
Anal Chem. 1983 Jan;55(1):54-6. doi: 10.1021/ac00252a017.
5
Comparison of methods for the determination of salicylic acid in buffered aspirin tablets.缓冲阿司匹林片中水杨酸测定方法的比较
J Pharm Sci. 1969 Jan;58(1):120-2. doi: 10.1002/jps.2600580128.
6
Fluorometric determination of salicylic acid in buffered aspirin products.缓冲阿司匹林产品中水杨酸的荧光测定法。
J Pharm Sci. 1971 Jan;60(1):114-6. doi: 10.1002/jps.2600600123.
7
Fluorescence of acetylsalicylic acid in solution and its measurement in presence of salicylic acid.溶液中乙酰水杨酸的荧光及其在水杨酸存在下的测量。
Anal Chem. 1970 May;42(6):656-9. doi: 10.1021/ac60288a032.
8
Fluorometric determination of salicylic acid in aspirin products including noninterfering, interfering, and buffered substances.荧光法测定阿司匹林产品中水杨酸的含量,包括无干扰、有干扰和缓冲物质。
J Pharm Sci. 1970 Mar;59(3):397-400. doi: 10.1002/jps.2600590328.
9
Determination of the decomposition of aspirin.
J Pharm Sci. 1970 Aug;59(8):1053-79. doi: 10.1002/jps.2600590802.
10
Determination of free salicylic acid in buffered aspirin tablets.缓冲阿司匹林片中游离水杨酸的测定。
J Pharm Sci. 1968 Apr;57(4):631-3. doi: 10.1002/jps.2600570418.