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严重多虑平中毒——两例报告

Severe dothiepin intoxication--a report of two cases.

作者信息

Bloodworth L, Wilson A, Collins P, Rainford D J

出版信息

Postgrad Med J. 1984 Jun;60(704):442-4. doi: 10.1136/pgmj.60.704.442.

DOI:10.1136/pgmj.60.704.442
PMID:6462990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2417882/
Abstract

Two patients with severe dothiepin intoxication are described. The management of these cases is discussed and we draw attention to the prolonged elimination half-life of dothiepin and its metabolites, and the implication for treatment.

摘要

本文描述了两名严重多虑平中毒患者。讨论了这些病例的处理方法,并提请注意多虑平及其代谢产物的消除半衰期延长以及对治疗的影响。

相似文献

1
Severe dothiepin intoxication--a report of two cases.严重多虑平中毒——两例报告
Postgrad Med J. 1984 Jun;60(704):442-4. doi: 10.1136/pgmj.60.704.442.
2
[Dosulepin poisoning].[多塞平中毒]
Beitr Gerichtl Med. 1987;45:213-6.
3
[Prothiadene intoxication in a 5-year-old boy].[一名5岁男孩的普罗噻吨中毒]
Cesk Pediatr. 1979 Jun;34(6):345-6.
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Sodium bicarbonate and hyperventilation in treating an infant with severe overdose of tricyclic antidepressant.碳酸氢钠与过度通气治疗三环类抗抑郁药严重过量的婴儿
Br Med J (Clin Res Ed). 1984 Jun 16;288(6433):1800-1. doi: 10.1136/bmj.288.6433.1800-a.
5
Simultaneous measurement of dothiepin and its major metabolites in plasma and whole blood by gas chromatography-mass fragmentography.采用气相色谱-质谱碎片分析法同时测定血浆和全血中多塞平及其主要代谢物。
J Chromatogr. 1981 Mar 13;222(3):399-408. doi: 10.1016/s0378-4347(00)84140-7.
6
Blood and plasma concentrations of dothiepin and its major metabolites and clinical response.多塞平及其主要代谢物的血液和血浆浓度与临床反应。
J Affect Disord. 1982 Mar;4(1):41-8. doi: 10.1016/0165-0327(82)90018-0.
7
Ipecacuanha.吐根
Arch Emerg Med. 1986 Jun;3(2):151-2. doi: 10.1136/emj.3.2.151.
8
[Fatal poisoning of a 3-year-old girl with Prothiaden Spofa].[一名3岁女童因服用司米安(Prothiaden Spofa)导致致命中毒]
Cesk Pediatr. 1978 Jul;33(7):406-7.
9
[Hypertonic sodium chloride in the treatment of tricyclic antidepressive poisoning].[高渗氯化钠治疗三环类抗抑郁药中毒]
Ugeskr Laeger. 1987 Mar 30;149(14):915-6.
10
Clinical pharmacokinetics of dothiepin. Single-dose kinetics in patients and prediction of steady-state concentrations.
Clin Pharmacokinet. 1983 Mar-Apr;8(2):179-85. doi: 10.2165/00003088-198308020-00004.

引用本文的文献

1
Extracorporeal treatment for tricyclic antidepressant poisoning: recommendations from the EXTRIP Workgroup.三环类抗抑郁药中毒的体外治疗:EXTRIP工作组的建议
Semin Dial. 2014 Jul-Aug;27(4):381-9. doi: 10.1111/sdi.12227. Epub 2014 Apr 9.

本文引用的文献

1
Clinical interpretation of pharmacokinetic data on dothiepin hydrochloride (Dosulepin, Prothiaden).盐酸多塞平(多虑平,普罗替林)药代动力学数据的临床解读
J Int Med Res. 1981;9(2):98-102. doi: 10.1177/030006058100900202.
2
Haemoperfusion in tricyclic antidepressant poisoning.
Lancet. 1980 Jan 19;1(8160):155.
3
Antidepressant blood levels in acute overdose.急性过量用药时的抗抑郁药血药浓度。
Postgrad Med J. 1976 Nov;52(613):687-8. doi: 10.1136/pgmj.52.613.687.
4
Hemoperfusion in the treatment of amitriptyline intoxication.血液灌流治疗阿米替林中毒
Trans Am Soc Artif Intern Organs. 1978;24:699-703.
5
Haemoperfusion in treatment of drug intoxication.血液灌流在药物中毒治疗中的应用
Br Med J. 1978 Jan 21;1(6106):174. doi: 10.1136/bmj.1.6106.174.
6
High performance liquid chromatographic determination of dothiepin and northiaden in human plasma and serum.高效液相色谱法测定人血浆和血清中的多塞平及去甲替林
J Int Med Res. 1977;5(6):387-90. doi: 10.1177/030006057300100201.
7
Pharmacokinetics of haemoperfusion for drug overdose.药物过量血液灌流的药代动力学
Clin Pharmacokinet. 1979 Sep-Oct;4(5):329-54. doi: 10.2165/00003088-197904050-00001.
8
Effect of activated charcoal on absorption of nortriptyline.活性炭对去甲替林吸收的影响。
Lancet. 1977 Dec 10;2(8050):1203-5. doi: 10.1016/s0140-6736(77)90440-8.