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幼儿局部应用抗生素治疗烧伤后出现的耳聋及生化失衡。6例报告。

Deafness and biochemical imbalance after burns treatment with topical antibiotics in young children. Report of 6 cases.

作者信息

Bamford M F, Jones L F

出版信息

Arch Dis Child. 1978 Apr;53(4):326-9. doi: 10.1136/adc.53.4.326.

Abstract

Six children are described in whom deafness followed treatment of full thickness burns with topical antibiotic spray containing neomycin. 3 children developed hypocalcaemic tetany, and were shown to have a metabolic disorder involving hypocalcaemia, hypomagnesaemia, and hypokalaemia. The dangers of treating burns with topical ototoxic and nephrotoxic antibiotics are emphasised.

摘要

本文描述了6名儿童,他们在使用含有新霉素的局部抗生素喷雾剂治疗全层烧伤后出现了耳聋。3名儿童发生了低钙性手足搐搦,检查发现存在涉及低钙血症、低镁血症和低钾血症的代谢紊乱。文中强调了使用局部耳毒性和肾毒性抗生素治疗烧伤的危险性。

相似文献

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Neomycin ototoxicity.
Ann Otol Rhinol Laryngol. 1978 Mar-Apr;87(2 Pt 1):211-5. doi: 10.1177/000348947808700211.
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Deafness after topical neomycin.局部应用新霉素后耳聋。
Br Med J. 1970 Apr 11;2(5701):114. doi: 10.1136/bmj.2.5701.114.

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Identification of impaired hearing in early childhood.幼儿期听力受损的识别。
Can Med Assoc J. 1979 Sep 8;121(5):529-32, 535-6, 538 passim.

本文引用的文献

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Polymyxin, colistin and bacitracin.多粘菌素、黏菌素和杆菌肽。
Pediatr Clin North Am. 1961 Nov;8:1057-71. doi: 10.1016/s0031-3955(16)31193-2.

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