Division of Toxicology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Clin Toxicol (Phila). 2010 Nov;48(9):953-5. doi: 10.3109/15563650.2010.533676.
Although hydrofluoric (HF) acid burns may cause extensive tissue damage, severe systemic toxicity is not common after mild dermal exposure.
A 36-year-old worker suffered a first-degree burn of 3% of his total body surface area as a result of being splashed on the right thigh with 20% HF acid. Immediate irrigation and topical use of calcium gluconate gel prevented local injury. However, the patient developed hypocalcemia and hypomagnesemia, hypokalemia, bradycardia, and eventually had asystole at 16 h post-exposure, which were unusual findings. He was successfully resuscitated by administration of calcium, magnesium, and potassium.
This report highlights a late risk of HF acid dermal exposure.
尽管氢氟酸(HF)酸烧伤可能会导致广泛的组织损伤,但在轻度皮肤暴露后,严重的全身毒性并不常见。
一名 36 岁的工人因右大腿被 20%HF 酸溅到,导致全身面积的 3%受到一度烧伤。立即进行冲洗和局部使用葡萄糖酸钙凝胶防止了局部损伤。然而,患者在暴露后 16 小时出现低钙血症和低镁血症、低钾血症、心动过缓,最终出现心搏停止,这些都是不常见的发现。通过给予钙、镁和钾,患者成功复苏。
本报告强调了 HF 酸皮肤暴露的晚期风险。