Khersonskaia R Ia, Rogotskaia L T
Zh Mikrobiol Epidemiol Immunobiol. 1984 Jun(6):73-6.
The complex clinico-epidemiological and laboratory surveys of the children and the staff in 71 institutions for children of preschool age were made at the period of increased viral hepatitis morbidity in these institutions, and the dynamic observations of 11 children's institutions having children with prolonged HBs-antigenemia were carried out. In the foci of viral hepatitis the level of antigenemia in the children and the staff exceeded (p less than 0.01) that in the control group. The dynamic observations (lasting up to 6 years) of the groups containing HBsAg-carriers revealed that 6 children, previously HBsAg-negative, showed a short-term HBs-antigenemia in the absence of any evidence of the parenteral (instrumental) route of infection. This fact indicates that the role of HBsAg-carriers as the possible sources contributing to the transfer of hepatitis B through everyday contacts in children's institutions cannot be ruled out. Periodic clinico-epidemiological and laboratory surveys of groups with HBsAg-carriers are recommended.
在这些机构中病毒性肝炎发病率上升期间，对71所学龄前儿童机构中的儿童和工作人员进行了复杂的临床流行病学和实验室调查，并对11所存在儿童长期乙肝表面抗原血症的儿童机构进行了动态观察。在病毒性肝炎疫源地，儿童和工作人员的抗原血症水平超过（p<0.01）对照组。对乙肝表面抗原携带者组进行的动态观察（持续长达6年）显示，6名先前乙肝表面抗原阴性的儿童在没有任何经肠外（器械）感染途径证据的情况下出现了短期乙肝表面抗原血症。这一事实表明，不能排除乙肝表面抗原携带者作为可能通过儿童机构日常接触传播乙型肝炎的传染源的作用。建议对乙肝表面抗原携带者组进行定期的临床流行病学和实验室调查。
