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[乙型肝炎病毒表面抗原(HBsAg)携带者的流行病学特征及重要性]

[Epidemiological characteristics and the importance of carriers of the surface antigen of the hepatitis B virus (HBsAg)].

作者信息

Mukomolov S L, Anan'ev V A, Shliakhtenko L I, Nechaev V V, Evdokimova T V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1984 Dec(12):76-80.

PMID:6241402
Abstract

The occurrence of HBsAg carriership in Leningrad has been found to be 1.4% according to the results of countercurrent immunoelectroosmophoresis (CIEO) and 2.1% according to the results of the passive hemagglutination (PHA) test. In children HBsAg occurs with higher frequency: 1.9% according to the results of CIEO and 3.4% according to the results of the PHA test. The latter test reveals HBsAg carriers more completely, especially in women who have usually less pronounced antigenemia than men. Most of chronic HBsAg carriers are patients with chronic forms of hepatitis B (chronic active hepatitis and chronic persistent hepatitis); frequently they become the source of infection among their relatives under the conditions of family contacts. A complex of antiepidemic measures is necessary in the foci of chronic HBsAg carriership.

摘要

根据对流免疫电渗析法(CIEO)的结果,列宁格勒HBsAg携带者的发生率为1.4%,而根据被动血凝试验(PHA)的结果则为2.1%。在儿童中,HBsAg出现的频率更高:根据CIEO的结果为1.9%,根据PHA的结果为3.4%。后一种检测方法能更全面地发现HBsAg携带者,尤其是在抗原血症通常比男性不那么明显的女性中。大多数慢性HBsAg携带者是慢性乙型肝炎(慢性活动性肝炎和慢性持续性肝炎)患者;在家庭接触的情况下,他们经常成为其亲属中的感染源。在慢性HBsAg携带者聚集区,有必要采取一系列防疫措施。

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1
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Zh Mikrobiol Epidemiol Immunobiol. 1984 Dec(12):76-80.
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