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持续动静脉血液滤过在重症医学中的应用。

The use of continuous arteriovenous hemofiltration in intensive care medicine.

作者信息

Schetz M, Lauwers P, Ferdinande P, Van de Walle J

出版信息

Acta Anaesthesiol Belg. 1984 Mar;35(1):67-78.

PMID:6464635
Abstract

Acute renal failure still remains an important and challenging problem in the ICU. Hemodialysis is not always feasible because of hemodynamic instability in critically ill patients. In this circumstances continuous arteriovenous hemofiltration (CAVH) can be an efficient alternative as this method has less detrimental hemodynamic effects. Moreover, within certain limitations, CAVH proves to be an effective "artificial kidney" (control of body fluid, electrolyte and acid-base homeostasis and uremia) and this without serious side-effects. Special emphasis is made on the problem of anticoagulation, which can cause life-threatening complications in posttraumatic and surgical patients. A protamine infusion on the venous line can diminish these complications.

摘要

急性肾衰竭在重症监护病房(ICU)仍然是一个重要且具有挑战性的问题。由于重症患者存在血流动力学不稳定的情况,血液透析并不总是可行的。在这种情况下,连续性动静脉血液滤过(CAVH)可以成为一种有效的替代方法,因为该方法对血流动力学的不利影响较小。此外,在一定限度内,CAVH被证明是一种有效的“人工肾”(可控制体液、电解质和酸碱平衡以及尿毒症),而且没有严重的副作用。文中特别强调了抗凝问题,抗凝在创伤后和外科手术患者中可能导致危及生命的并发症。在静脉管路中输注鱼精蛋白可以减少这些并发症。

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