Song W O, Chan G M, Wyse B W, Hansen R G
Am J Clin Nutr. 1984 Aug;40(2):317-24. doi: 10.1093/ajcn/40.2.317.
Seventeen lactating women who delivered preterm infants (between 28 to 34 wk of gestational age) and 26 nursing mothers of term infants participated in the study. Each term mother kept a record of 2-day dietary intakes, collected urines for 2 days, and provided fore and hind milk samples and a fasting blood sample at 2 and 12 wk postpartum. Each of preterm women provided fore and hind milk samples once a week for 16 wk starting 2 wk postpartum. The method of determining pantothenic acid content in milk samples was validated, and the vitamin was quantitated by the radioimmunoassay. The average pantothenate levels in fore and hind samples of preterm milk (3.31 and 3.72 micrograms/ml, respectively) were significantly (p less than 0.05) higher than those of term milk (2.64 and 2.48 micrograms/ml, respectively). No significant change was observed in pantothenic acid content within a feeding or with the progress of nursing in both groups. The vitamin content of human milk was compared with the minimum requirement of the Infant Formula Act of 1980. The pantothenate level in term milk was significantly (p less than 0.05) correlated with the vitamin level in maternal circulation and with that of the dietary intake and urinary excretion.
17名早产（胎龄在28至34周之间）产妇和26名足月产婴儿的哺乳期母亲参与了该研究。每位足月产母亲记录了2天的饮食摄入量，收集了2天的尿液，并在产后2周和12周提供了前奶和后奶样本以及空腹血样。每位早产产妇从产后2周开始，每周提供一次前奶和后奶样本，持续16周。测定奶样中泛酸含量的方法经过验证，该维生素通过放射免疫测定法定量。早产奶前奶和后奶样本中的平均泛酸盐水平（分别为3.31和3.72微克/毫升）显著高于足月产奶（分别为2.64和2.48微克/毫升）（p<0.05）。两组在一次喂奶过程中或随着哺乳进程，泛酸含量均未观察到显著变化。将人乳中的维生素含量与1980年《婴儿配方奶粉法案》的最低要求进行了比较。足月产奶中的泛酸盐水平与母体循环中的维生素水平、饮食摄入量以及尿排泄量显著相关（p<0.05）。
