Hartz J W, Buss D H, White D R, Bond M G, Scharyj M
Am J Clin Pathol. 1984 Sep;82(3):354-9. doi: 10.1093/ajcp/82.3.354.
A 78-year-old white male patient presented with anemia characterized by marked elliptocytosis and schistocytosis. Other morphologic findings in the peripheral blood and marrow were diagnostic of hematopoietic dysplasia (preleukemic syndrome). Five years previously elliptocytosis and schistocytosis were not present, and the only features suggesting hematopoietic dysplasia were significant numbers of micromegakaryocytes in the marrow and rare giant platelets with giant granules in the peripheral blood. The features of this case suggest that acquired marked elliptocytosis and schistocytosis may be an unusual manifestation of hematopoietic dysplasia.
一名78岁的白人男性患者出现贫血，其特征为显著的椭圆形红细胞增多症和裂红细胞症。外周血和骨髓中的其他形态学发现可诊断为造血发育异常（白血病前期综合征）。五年前不存在椭圆形红细胞增多症和裂红细胞症，提示造血发育异常的唯一特征是骨髓中存在大量微型巨核细胞以及外周血中罕见的带有巨大颗粒的巨型血小板。该病例的特征表明，获得性显著椭圆形红细胞增多症和裂红细胞症可能是造血发育异常的一种不寻常表现。
