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饮食、肥胖与致命前列腺癌风险

Diet, obesity, and risk of fatal prostate cancer.

作者信息

Snowdon D A, Phillips R L, Choi W

出版信息

Am J Epidemiol. 1984 Aug;120(2):244-50. doi: 10.1093/oxfordjournals.aje.a113886.

Abstract

Findings described in this report are for 6,763 white male Seventh-day Adventists who completed a dietary questionnaire in 1960. Between 1960 and 1980 mortality data were collected on cohort members. Overweight men had a significantly higher risk of fatal prostate cancer than men near their desirable weight. The predicted relative risk of fatal prostate cancer was 2.5 for overweight men. Suggestive positive associations were also seen between fatal prostate cancer and the consumption of milk, cheese, eggs, and meat. There was an orderly dose-response between each of the four animal products and risk. The predicted relative risk of fatal prostate cancer was 3.6 for those who heavily consumed all four animal products. The results of this study and others suggest that animal product consumption and obesity may be risk factors for fatal prostate cancer.

摘要

本报告中描述的研究结果来自6763名白人男性基督复临安息日会信徒,他们于1960年完成了一份饮食调查问卷。在1960年至1980年期间,收集了该队列成员的死亡率数据。超重男性患致命前列腺癌的风险显著高于体重接近理想水平的男性。超重男性患致命前列腺癌的预测相对风险为2.5。在致命前列腺癌与牛奶、奶酪、鸡蛋和肉类的消费之间也发现了提示性的正相关关系。这四种动物产品中的每一种与风险之间都存在有序的剂量反应关系。大量食用所有四种动物产品的人患致命前列腺癌的预测相对风险为3.6。这项研究和其他研究的结果表明,食用动物产品和肥胖可能是致命前列腺癌的风险因素。

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