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胆碱甲基基团在瘤胃中通过三甲胺转化为甲烷。

Conversion of choline methyl groups through trimethylamine into methane in the rumen.

作者信息

Neill A R, Grime D W, Dawson R M

出版信息

Biochem J. 1978 Mar 15;170(3):529-35. doi: 10.1042/bj1700529.

DOI:10.1042/bj1700529
PMID:646798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1183928/
Abstract
  1. Choline methyl groups were rapidly metabolized to trimethylamine by rumen micro-organisms. 2. Trimethylamine was further metabolized to methane, but this system was more easily saturated by an excess of substrate, so that trimethylamine accumulated in the rumen of the fed animal. 3. Although trimethylamine was the only intermediate isolated in the conversion of the methyl groups of choline into methane, methylamine also served as a substrate for methane production. 4. The methyl group of methionine was also converted into methane by rumen fluid, but the methyl groups of carnitine were not.
摘要
  1. 胆碱甲基基团被瘤胃微生物迅速代谢为三甲胺。2. 三甲胺进一步代谢为甲烷,但该系统更容易因底物过量而饱和,从而导致三甲胺在采食动物的瘤胃中积累。3. 虽然三甲胺是胆碱甲基基团转化为甲烷过程中唯一分离出的中间产物,但甲胺也可作为甲烷生成的底物。4. 蛋氨酸的甲基基团也可被瘤胃液转化为甲烷,但肉碱的甲基基团则不能。

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