Friedman L, Lewis P J, Clifton P, Bulpitt C J
Br Med J. 1978 May 13;1(6122):1235-7. doi: 10.1136/bmj.1.6122.1235.
A retrospective study of 12 461 single births confirmed an association between maternal oxytocin infusion and neonatal jaundice. The effect of oxytocin on jaundice was independent of gestational age at birth, sex, race, epidural anaesthesia, method of delivery, and birth weight, each of which was significantly associated with neonatal jaundice. The effect of oxytocin was, however, small, producing a calculated mean increase in peak plasma bilirubin concentration of 8.6 mumol/1 (0.5 mg/100 ml); this excess was independent of sex and less than the effect of the baby being born one week earlier.
一项针对12461例单胎分娩的回顾性研究证实，产妇输注催产素与新生儿黄疸之间存在关联。催产素对黄疸的影响独立于出生时的孕周、性别、种族、硬膜外麻醉、分娩方式和出生体重，而这些因素均与新生儿黄疸显著相关。然而，催产素的影响较小，导致血浆胆红素峰值浓度的计算平均增加量为8.6微摩尔/升（0.5毫克/100毫升）；这种增加与性别无关，且小于婴儿早产一周的影响。
