缩宫素的使用与新生儿黄疸的发生率
Use of oxytocin and incidence of neonatal jaundice.
作者信息
Chalmers I, Campbell H, Turnbull A C
出版信息
Br Med J. 1975 Apr 19;2(5963):116-8. doi: 10.1136/bmj.2.5963.116.
Abstract
A retrospective controlled study using data from the Cardiff Births Survey examined a possible relation between oxytocin administration to induce or accelerate labour and the subsequent development of neonatal jaundice. Among 10 591 infants born in Cardiff between 1970 and 1972 the incidence of neonatal jaundice was higher in infants born after oxytocin administration than among others. Analysis by gestational age at delivery, birth weight, Apgar score, length of labour, sedative and analgesic therapy during labour, and suppression of lactation showed that this association held within all these categories except among small immature infants, who are at high risk of jaundice in any case.
摘要
一项利用加的夫出生调查数据进行的回顾性对照研究，探讨了使用催产素引产或加速分娩与随后新生儿黄疸发生之间的可能关系。在1970年至1972年于加的夫出生的10591名婴儿中，使用催产素后出生的婴儿患新生儿黄疸的发生率高于其他婴儿。按分娩时的孕周、出生体重、阿氏评分、产程、分娩期间的镇静和镇痛治疗以及泌乳抑制进行分析，结果显示，除了本身就有很高黄疸风险的未成熟小婴儿外，在所有这些类别中均存在这种关联。
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本文引用的文献
1
Statistical aspects of the analysis of data from retrospective studies of disease.疾病回顾性研究数据的统计分析方面
J Natl Cancer Inst. 1959 Apr;22(4):719-48.
2
[Influence of oxytocics on the neonatal jaundice].[缩宫素对新生儿黄疸的影响]
Arch Gynakol. 1971 Jun 4;211(1):144-6. doi: 10.1007/BF00682863.
3
Effect on neonatal jaundice of oestrogens and progestogens taken before and after conception.孕前及孕后服用雌激素和孕激素对新生儿黄疸的影响。
Br Med J. 1973 Sep 22;3(5881):605-7. doi: 10.1136/bmj.3.5881.605.
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Letter: Neonatal jaundice and maternal oxytocin infusion.信函：新生儿黄疸与产妇催产素输注
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