Augensen K, Bergsjø P, Eikeland T, Askvik K, Carlsen J
Br Med J (Clin Res Ed). 1987 May 9;294(6581):1192-5. doi: 10.1136/bmj.294.6581.1192.
In a prospective randomised study of mothers referred for prolonged pregnancy (around the 42nd week) 214 (group 1) were submitted to attempted induction of labour and 195 (group 2) assigned to continue for a further week without intervention. Strict selection criteria were used for the certainty of term. Mothers in group 2 were given regular non-stress tests to ensure fetal wellbeing, as were those in group 1 in whom induction failed. In group 1, 48 (23%) out of 210 first attempted inductions failed. In group 2, 135 (69%) of the births started spontaneously as compared with 38 (18%) in group 1. The mean duration of labour was 7.5 hours in each group. There was no significant difference in incidence of operative delivery, use of analgesics, or signs of perinatal asphyxia. Significantly more children in group 1 needed phototherapy for hyperbilirubinaemia. There was a clustering of births in the late afternoon and evening, which was most pronounced in group 1. A policy of vigilant non-intervention up to the 44th completed week of pregnancy does not appear to jeopardize mother or fetus.
在一项针对延期妊娠（约第42周）母亲的前瞻性随机研究中，214名母亲（第1组）接受了引产尝试，195名母亲（第2组）被分配在无干预情况下继续等待一周。为确保孕周准确，采用了严格的选择标准。第2组的母亲接受定期无应激试验以确保胎儿健康，第1组引产失败的母亲也同样接受该试验。在第1组中，210次首次引产尝试中有48次（23%）失败。在第2组中，135例（69%）分娩自然发动，而第1组中这一比例为38例（18%）。每组的平均产程均为7.5小时。手术分娩发生率、镇痛药使用情况或围产期窒息体征方面无显著差异。第1组中因高胆红素血症需要光疗的儿童明显更多。分娩集中在下午晚些时候和晚上，在第1组中最为明显。在妊娠满44周前采取警惕性非干预政策似乎不会危及母亲或胎儿。
