同期低位破膜与缩宫素输注及其他母体因素对新生儿黄疸的影响：一项前瞻性研究。
Influence of simultaneous low amniotomy and oxytocin infusion and other maternal factors on neonatal jaundice: a prospective study.
作者信息
Chew W C, Swann I L
出版信息
Br Med J. 1977 Jan 8;1(6053):72-3. doi: 10.1136/bmj.1.6053.72.
Abstract
In a prospective study of 196 consecutive single births a significant increase in serum bilirubin concentrations was found in infants born after low amniotomy induction and oxytocin infusion compared with those born spontaneously. This relationship was not dose-dependent and may have been associated with artificial interruption of pregnancy rather than the oxytocin itself. Infants delivered after spontaneous labour accelerated by oxytocin showed no such increase. The hormonal surge at the spontaneous onset of labour may affect fetal enzyme induction, but other factors, such as methods of infant feeding and oral contraceptive use, were found not to be significant.
摘要
在一项对196例连续单胎分娩的前瞻性研究中，发现与自然分娩的婴儿相比，低位人工破膜引产和静脉滴注缩宫素后出生的婴儿血清胆红素浓度显著升高。这种关系不依赖剂量，可能与妊娠的人工干预有关，而非缩宫素本身。缩宫素加速自然分娩后出生的婴儿未出现这种升高。分娩自然发动时的激素激增可能影响胎儿酶的诱导，但发现其他因素，如婴儿喂养方式和口服避孕药的使用，并无显著影响。
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本文引用的文献
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Neonatal jaundice. A review.新生儿黄疸。一篇综述。
Am J Dis Child. 1961 Jan;101:87-127. doi: 10.1001/archpedi.1961.04020020089014.
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Neonatal hyperbilirubinaemia and breast feeding.新生儿高胆红素血症与母乳喂养
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Induction of labour by amniotomy and simultaneous Syntocinon infusion.人工破膜引产并同时输注缩宫素。
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Induction of labour. II. Intravenous oxytocin infusion.引产。二、静脉滴注缩宫素。
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Automatic oxytocin infusion equipment for induction of labour.用于引产的自动催产素输注设备。
J Obstet Gynaecol Br Commonw. 1970 Jul;77(7):594-602. doi: 10.1111/j.1471-0528.1970.tb03576.x.
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Breast-milk jaundice and oral contraceptives.母乳性黄疸与口服避孕药
Br Med J. 1971 Nov 13;4(5784):403-4. doi: 10.1136/bmj.4.5784.403.
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Drug therapy in labour and reduction of induction-delivery interval.分娩期药物治疗与缩短引产-分娩间隔时间
Proc R Soc Med. 1972 Aug;65(8):698-9. doi: 10.1177/003591577206500816.
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