Brockes J P
Science. 1984 Sep 21;225(4668):1280-7. doi: 10.1126/science.6474177.
Regeneration of the amphibian limb after amputation depends on division of blastemal cells, the progenitor cells of the regenerate. This division is controlled, at least in the early stages of regeneration, by the nerve supply to the blastema. A monoclonal antibody to newt blastema cells has provided evidence that Schwann cells and muscle fibers contribute to the blastema, and identifies blastemal cells whose division is persistently dependent on the nerve. Glial growth factor, a molecule identified by its action on rat Schwann cells, is present in the newt blastema and is lost on denervation.
两栖动物肢体截肢后的再生取决于芽基细胞（即再生组织的祖细胞）的分裂。至少在再生的早期阶段，这种分裂是由芽基的神经供应控制的。一种针对蝾螈芽基细胞的单克隆抗体提供了证据，表明雪旺细胞和肌纤维对芽基有贡献，并识别出其分裂持续依赖神经的芽基细胞。神经胶质生长因子是一种因其对大鼠雪旺细胞的作用而被鉴定出来的分子，它存在于蝾螈芽基中，去神经支配后会消失。
