Kayembe K N, Sasahara M, Hazama F
Stroke. 1984 Sep-Oct;15(5):846-50. doi: 10.1161/01.str.15.5.846.
In order to obtain information about the relationship between variations in the circle of Willis and aneurysms, 44 complete circles of Willis with aneurysm were studied macroscopically. The incidence of variations was significantly higher in the aneurysm series than in the control circles without aneurysm. There was a definite correlation between asymmetric proximal segments of the anterior cerebral artery and aneurysms of the anterior communicating artery, and a tendency to correlation was found in the case of asymmetric posterior communicating arteries and aneurysms on the internal carotid artery-posterior communicating artery junction. In the light of these findings it seems likely that through hemodynamic changes variation in the circle of Willis plays some role in the development of cerebral aneurysms.
为了获取有关 Willis 环变异与动脉瘤之间关系的信息，对 44 个伴有动脉瘤的完整 Willis 环进行了宏观研究。动脉瘤组 Willis 环变异的发生率显著高于无动脉瘤的对照组。大脑前动脉近端不对称节段与前交通动脉瘤之间存在明确的相关性，并且在后交通动脉不对称及颈内动脉 - 后交通动脉交界处的动脉瘤病例中发现有相关趋势。根据这些发现，Willis 环的变异似乎很可能通过血流动力学变化在脑动脉瘤的发生发展中发挥一定作用。
