Keil J E, Loadholt C B, Weinrich M C, Sandifer S H, Boyle E
Am Heart J. 1984 Sep;108(3 Pt 2):779-86. doi: 10.1016/0002-8703(84)90671-9.
We studied a cohort of 2275 blacks and whites of both sexes in Charleston County, South Carolina, during the period of 1960-1961 to 1974-1975. There were 93 prevalent cases of coronary heart disease (CHD) at intake, and 317 new cases occurred by 1975 in persons originally free of CHD. White males had the highest incidence rates for all types of CHD and acute myocardial infarction (AMI). Black males and black females had the next highest rates. The incidence of angina pectoris in black females was double the rate in white females and five times the rate in white males. The rate of sudden death in black males was two and one-half times the rate in black females, three times the rate in white males, and four times the rate in white females. One hundred and one black males who had been selected on the basis of high socioeconomic status (SES) had AMI and CHD rates half that of other black males. None of the high SES black males experienced angina pectoris, AMI death, or sudden death during the observation period.
1960年至1961年至1974年至1975年期间，我们对南卡罗来纳州查尔斯顿县的2275名黑人及白人男女组成的队列进行了研究。入组时共有93例冠心病（CHD）患者，到1975年，最初无冠心病的人群中有317例新发病例。白人男性各类冠心病和急性心肌梗死（AMI）的发病率最高。黑人男性和黑人女性的发病率次之。黑人女性心绞痛的发病率是白人女性的两倍，是白人男性的五倍。黑人男性的猝死率是黑人女性的2.5倍，是白人男性的3倍，是白人女性的4倍。101名基于高社会经济地位（SES）入选的黑人男性，其AMI和CHD发病率是其他黑人男性的一半。在观察期内，高SES黑人男性均未出现心绞痛、AMI死亡或猝死情况。
