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SERUM LIPIDS AND LIPOPROTEINS DURING PREGNANCY.孕期的血清脂质与脂蛋白
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Lipoprotein[a] concentrations and apolipoprotein[a] phenotypes in Caucasians and African Americans. The CARDIA study.白种人和非裔美国人的脂蛋白[a]浓度及载脂蛋白[a]表型。CARDIA研究。
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Serum lipids, lipoproteins and apolipoproteins in pregnant non-diabetic patients.非糖尿病孕妇的血清脂质、脂蛋白和载脂蛋白
J Clin Pathol. 1994 Aug;47(8):728-31. doi: 10.1136/jcp.47.8.728.
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High-density lipoprotein cholesterol in blacks and whites: potential ramifications for coronary heart disease.黑人和白人中的高密度脂蛋白胆固醇：对冠心病的潜在影响。
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Incidence of coronary heart disease in blacks in Charleston, South Carolina.南卡罗来纳州查尔斯顿黑人冠心病的发病率。
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Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.无需使用制备性超速离心机来估算血浆中低密度脂蛋白胆固醇的浓度。
Clin Chem. 1972 Jun;18(6):499-502.
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Serum lipids in young women before, during, and after pregnancy.年轻女性在怀孕前、怀孕期间及产后的血脂情况。
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非洲裔和高加索裔孕妇脂质及脂蛋白代谢的种族差异。

Ethnic differences in lipid and lipoprotein metabolism in pregnant women of African and Caucasian origin.

作者信息

Koukkou E, Watts G F, Mazurkiewicz J, Lowy C

机构信息

Department of Endocrinology and Chemical Pathology, St Thomas's Hospital (UMDS), London.

出版信息

J Clin Pathol. 1994 Dec;47(12):1105-7. doi: 10.1136/jcp.47.12.1105.

DOI:10.1136/jcp.47.12.1105
PMID:7876384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC502203/
Abstract

AIMS

To investigate differences in serum lipid, lipoprotein and apolipoprotein concentrations in pregnant women of different ethnic origin.

METHODS

Serum lipid, lipoprotein and apolipoprotein concentrations were measured in 232 women (114 Caucasians, 118 Africans/Afro-Caribbeans), who presented consecutively for screening for gestational diabetes in the third trimester of pregnancy.

RESULTS

African/Afro-Caribbean pregnant women had lower serum concentrations of total cholesterol, low density lipoprotein cholesterol, triglycerides, and apolipoprotein B and higher high density lipoprotein cholesterol and Lp(a) lipoprotein concentrations compared with Caucasian women. Apolipoprotein A1 concentrations were similar in the two groups. The differences were not attributable to differences in weight, age, parity, or postload plasma glucose levels.

CONCLUSION

Ethnic origin is an important determinant of serum lipid, lipoprotein and apolipoprotein concentrations during pregnancy.

摘要

目的

研究不同种族孕妇血清脂质、脂蛋白和载脂蛋白浓度的差异。

方法

对232名在妊娠晚期连续前来筛查妊娠期糖尿病的女性（114名白种人、118名非洲人/非裔加勒比人）进行血清脂质、脂蛋白和载脂蛋白浓度测定。

结果

与白种女性相比，非洲/非裔加勒比孕妇的总胆固醇、低密度脂蛋白胆固醇、甘油三酯和载脂蛋白B血清浓度较低，而高密度脂蛋白胆固醇和Lp(a)脂蛋白浓度较高。两组的载脂蛋白A1浓度相似。这些差异并非由体重、年龄、产次或负荷后血糖水平的差异所致。

结论

种族是孕期血清脂质、脂蛋白和载脂蛋白浓度的重要决定因素。