Ronayne de Ferrer P A, Slobodianik N H, López N, Sambucetti M E, Sanahuja J C
Am J Clin Nutr. 1984 Sep;40(3):465-7. doi: 10.1093/ajcn/40.3.465.
Little information is available on immunoglobulin content of milk from mothers of preterm babies. In this study we have measured IgA levels in samples from preterm and term mothers during the 1st month postpartum. The concentration of IgA tended to be constant in the preterm group (about 251 mg/dl) while it showed a decreasing trend in the term group (from 212.8 +/- 19.9 to 171.6 +/- 12.8 mg/dl). From day 10 onward IgA levels in preterm milk were significantly higher than in term milk (p less than 0.002). These findings support the idea that premature infants fed their own mothers' milk would benefit from more stable levels of IgA, at a time when their mucosal immune system is poorly developed.
关于早产婴儿母亲乳汁中免疫球蛋白含量的信息很少。在本研究中，我们测量了产后第1个月早产和足月母亲样本中的IgA水平。早产组中IgA浓度趋于恒定（约251mg/dl），而足月组则呈下降趋势（从212.8±19.9降至171.6±12.8mg/dl）。从第10天起，早产母乳中的IgA水平显著高于足月母乳（p<0.002）。这些发现支持了这样一种观点，即当早产儿的黏膜免疫系统发育不良时，喂养自己母亲的乳汁将受益于更稳定的IgA水平。
