Sagebiel R W, Chinn E K, Egbert B M
Am J Surg Pathol. 1984 Sep;8(9):645-53.
A clinical and histologic review of 90 patients with melanocytic lesions termed pigmented spindle cell nevi (PSCN) is reported. The lesions are small in surface diameter, sharply confined both clinically and histologically, and often occur on the proximal extremities of young adults. They are generally of recent onset, moderately to heavily pigmented, and made up of nests of spindled cells confined to the epidermis and papillary dermis. There were 30 male and 60 female patients. Their average age was 25.3 years (ranging from 2.5 to 56 years). Lesions were located on the extremities in 61 cases (67%). Follow-up was possible in 38 cases seen more than 6 months after histologic diagnosis and ranged up to 40 months (average 14 months). No local recurrence or distant spread was found. The importance of recognizing this lesion lies in differentiating it from malignant melanoma. Conservative but complete excision has resulted in no recorded instances of local recurrence or distant spread.
本文报告了对90例被称为色素性梭形细胞痣（PSCN）的黑素细胞病变患者的临床和组织学回顾。这些病变表面直径较小，在临床和组织学上界限清晰，常发生于年轻成年人的近端肢体。它们通常为近期发病，色素沉着中度至重度，由局限于表皮和乳头真皮的梭形细胞巢组成。患者中男性30例，女性60例。他们的平均年龄为25.3岁（范围为2.5至56岁）。61例（67%）病变位于四肢。组织学诊断后6个月以上就诊的38例患者得以随访，随访时间长达40个月（平均14个月）。未发现局部复发或远处转移。认识到这种病变的重要性在于将其与恶性黑色素瘤区分开来。保守但完整的切除术后未记录到局部复发或远处转移的病例。
