Lorenz L, Beaty B J, Aitken T H, Wallis G P, Tabachnick W J
Am J Trop Med Hyg. 1984 Jul;33(4):690-4. doi: 10.4269/ajtmh.1984.33.690.
Two colonies of Aedes aegypti were established from two independent collections from Vero Beach, Florida. Eleven sequential generations of the first colony were tested for variation in oral susceptibility to infection with yellow fever virus (YFV). Each generation was also assayed for genetic variability at seven enzyme loci using electrophoretic techniques. Significant differences in infection rates were detected between some generations. These differences were significantly correlated with genetic variation at the malate dehydrogenase locus. Seven generations from the second colony were examined simultaneously for variation in susceptibility to YFV. Significant differences were also detected between some of these generations. The results suggest that colonization may have an effect on the genetic and phenotypic variation in a mosquito strain, and that genetically based variation for susceptibility to infection with YFV occurs in populations of Ae. aegypti.
从佛罗里达州维罗海滩的两次独立采集建立了两个埃及伊蚊种群。对第一个种群的连续11代进行了口服感染黄热病病毒（YFV）易感性变异的检测。每一代还使用电泳技术检测了七个酶位点的遗传变异性。在某些代之间检测到感染率存在显著差异。这些差异与苹果酸脱氢酶位点的遗传变异显著相关。同时对第二个种群的七代进行了YFV易感性变异检测。在这些代中的一些代之间也检测到了显著差异。结果表明，种群建立可能对蚊种的遗传和表型变异有影响，并且埃及伊蚊种群中存在基于遗传的YFV感染易感性变异。
