Win 49375的抗菌谱
Antimicrobial spectrum of Win 49375.
作者信息
Jacobus N V, Tally F P, Barza M
出版信息
Antimicrob Agents Chemother. 1984 Jul;26(1):104-7. doi: 10.1128/AAC.26.1.104.
Abstract
Win 49375 had excellent activity against members of the family Enterobacteriaceae and staphylococcal species. Its activity against Pseudomonas aeruginosa was equal to that of gentamicin. Win 49375 had moderate activity against clostridia but little against Bacteroides fragilis. The drug showed a marked inoculum effect at 10(8) CFU/ml and a slight decrease in potency at pH 5.
摘要
Win 49375对肠杆菌科细菌和葡萄球菌属具有优异的活性。其对铜绿假单胞菌的活性与庆大霉素相当。Win 49375对梭菌属有中等活性，但对脆弱拟杆菌活性较弱。该药物在10⁸CFU/ml时显示出明显的接种物效应，在pH 5时效力略有下降。
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