Chan S Y, Tang L C, Chan P H, Tang G W, Ma H K
Arch Androl. 1984;12(1):17-24. doi: 10.3109/01485018409161142.
Seminal plasma prolactin (PRL) levels were determined in 224 semen samples collected from fertile and suspected infertile men, and their relationships with spermatozoal characteristics and fertilizing capacity in vitro were evaluated. PRL concentrations were similar in normospermic and oligospermic samples, but were significantly lower in azoospermic samples. PRL concentrations were significantly higher in samples with high spermatozoal motility than in those with low spermatozoal motility. There were no significant differences in PRL concentrations between normal-morphology and abnormal-morphology samples, and between high-fertilizing capacity and low-fertilizing capacity samples. A low degree of positive correlation was observed between the PRL concentration and the spermatozoal motility. There were no significant correlations between the PRL levels, the other spermatozoal characteristics, and the spermatozoal fertilizing capacity in vitro. These findings indicate that the seminal plasma PRL levels are significantly depressed in azoospermic subjects and suggest that the seminal plasma PRL may play a role in the maintenance of spermatozoal motility. Whether there is a potential function of prolactin in semen on spermatozoal fertilizing capacity, however, cannot be inferred from the present study.
对从生育能力正常和疑似不育男性收集的224份精液样本测定了精浆催乳素（PRL）水平，并评估了其与精子特征及体外受精能力的关系。正常精子样本和少精子样本中的PRL浓度相似，但无精子样本中的PRL浓度显著更低。精子活力高的样本中PRL浓度显著高于精子活力低的样本。正常形态样本与异常形态样本之间、高受精能力样本与低受精能力样本之间的PRL浓度无显著差异。PRL浓度与精子活力之间观察到低度正相关。PRL水平与其他精子特征及精子体外受精能力之间无显著相关性。这些发现表明无精子症患者的精浆PRL水平显著降低，并提示精浆PRL可能在维持精子活力中起作用。然而，从本研究无法推断催乳素在精液中对精子受精能力是否有潜在作用。
