Moster M L, Savino P J, Sergott R C, Bosley T M, Schatz N J
Arch Ophthalmol. 1984 Sep;102(9):1328-30. doi: 10.1001/archopht.1984.01040031078029.
Acquired sixth-nerve palsies are relatively rare in younger adults. We reexamined 49 patients, aged from 15 to 50 years, with isolated sixth-nerve palsies who were seen between 1972 and 1982 at the Wills Eye Hospital in Philadelphia. In this group, the following etiologies were encountered: vasculopathy (14 patients [29%]), tumors (eight patients [16%]), multiple sclerosis (six patients [12%]), presumed inflammation (four patients [8%]), trauma (three patients [6%]), postlumbar puncture (two patients [4%]), and orbital amyloidosis (one patient [2%]). Eleven patients (22%) had no determined cause of their sixth-nerve palsy. The implications for the clinical management of isolated sixth-nerve palsies in younger adults are discussed.
后天性第六神经麻痹在年轻成年人中相对少见。我们重新检查了49例年龄在15至50岁之间、患有孤立性第六神经麻痹的患者，这些患者于1972年至1982年间在费城的威尔斯眼科医院就诊。在这组患者中，发现了以下病因：血管病变（14例[29%]）、肿瘤（8例[16%]）、多发性硬化（6例[12%]）、推测为炎症（4例[8%]）、创伤（3例[6%]）、腰椎穿刺后（2例[4%]）和眼眶淀粉样变性（1例[2%]）。11例患者（22%）的第六神经麻痹病因未明确。本文讨论了年轻成年人孤立性第六神经麻痹临床管理的相关问题。
