Sordat B, Wang W R
Behring Inst Mitt. 1984 May(74):291-300.
Factors associated with the growth and progression of (human) tumor xenografts have been briefly reviewed. Intrinsic properties of tumor cells, most of them yet to be recognized, may interfere with multiple rejection processes and/or growth regulatory signals developed in various immunodeficient recipients. Using alternative hosts or new experimental conditions, it is hoped that the system can provide valuable information on the tumor invasive and metastasizing processes.
已对与（人类）肿瘤异种移植生长和进展相关的因素进行了简要综述。肿瘤细胞的内在特性（其中大多数尚未被认识）可能会干扰多种免疫缺陷受体中发生的排斥过程和/或生长调节信号。通过使用替代宿主或新的实验条件，有望该系统能提供有关肿瘤侵袭和转移过程的有价值信息。
