Stojković R, Hult K, Gamulin S, Plestina R
Biochem Int. 1984 Jul;9(1):33-8.
The binding properties of ochratoxin A to human and porcine plasma constituents were studied in vitro. Ochratoxin A was shown to bind to other plasma constituents with a considerably higher affinity than the earlier known nonspecific binding to plasma albumins. The association constant for the high affinity macromolecule (s) in human plasma was found to be 2.3 X 10(10) M-1 and for porcine plasma 0.59 X 10(10) M-1. The macromolecule (s) to which ochratoxin A binds more specifically than to albumins have not been identified, but their molecular weights were estimated by gel filtration to be 20 000.
在体外研究了赭曲霉毒素A与人及猪血浆成分的结合特性。结果表明，赭曲霉毒素A与其他血浆成分的结合亲和力远高于此前已知的与血浆白蛋白的非特异性结合。人血浆中高亲和力大分子的缔合常数为2.3×10¹⁰ M⁻¹，猪血浆中为0.59×10¹⁰ M⁻¹。尚未鉴定出赭曲霉毒素A比白蛋白更特异性结合的大分子，但通过凝胶过滤估计其分子量为20000。
