Oberai B, Adams C W, High O B
Atherosclerosis. 1984 Aug;52(2):185-90. doi: 10.1016/0021-9150(84)90116-3.
Arteriolar wall thickness was measured in cigarette smokers by means of eyepiece micrometry, paper planimetry and computerized planimetry. Myocardial and renal arterioles in such smokers showed significant thickening of their walls. This thickening was mainly attributable to an increase in collagen and smooth muscle. The adventitia of small to medium-sized intramyocardial coronary arteries showed an increase in collagen. Platelets are known to be more adhesive to the vessel wall in smokers. It is suggested that platelet-derived growth factor, released in the vessel wall, may promote proliferation of connective tissues, thus leading to the vascular thickening described.
通过目镜测微法、纸样面积测量法和计算机化面积测量法对吸烟者的小动脉壁厚度进行了测量。这类吸烟者的心肌和肾小动脉显示出明显的管壁增厚。这种增厚主要归因于胶原蛋白和平滑肌的增加。中小尺寸心肌内冠状动脉的外膜显示胶原蛋白增加。已知吸烟者的血小板对血管壁的黏附性更强。有人提出，血管壁中释放的血小板衍生生长因子可能会促进结缔组织的增殖，从而导致所述的血管增厚。
