Crawshaw J A, Mullen P E
Br J Psychiatry. 1984 Sep;145:300-3. doi: 10.1192/bjp.145.3.300.
The occasional abuse of anticholinergic drugs for their psychotropic and specifically hallucinogenic properties has been known for over a century, but benzhexol (trihexyphenidyl) abuse has only recently attracted attention in the literature, mainly in case reports. This paper reports on a study of 21 benzhexol abusers. They were a young, single, and disadvantaged group of polydrug abusers with poor employment, educational, and social skills, who abused benzhexol mainly for its euphorogenic properties. The two major diagnostic categories were antisocial personality disorder and schizophrenia. An unexpected finding was cognitive impairment persisting after acute intoxication.
一个多世纪以来，人们一直知道有人偶尔滥用抗胆碱能药物以获取其精神作用，特别是致幻特性，但苯海索（安坦）滥用只是最近才在文献中引起关注，主要是在病例报告中。本文报告了一项对21名苯海索滥用者的研究。他们是一群年轻、单身且处于不利地位的多药滥用者，就业、教育和社交技能较差，滥用苯海索主要是为了获得其欣快作用。两个主要诊断类别是反社会人格障碍和精神分裂症。一个意外发现是急性中毒后持续存在认知障碍。
