Kendall B, Stevens J
Br J Radiol. 1984 Sep;57(682):785-7. doi: 10.1259/0007-1285-57-681-785.
An open, non comparative study of cervical myelography in 68 adult patients using iohexol (Omnipaque) containing 300 mg I/ml is reported. Satisfactory visualisation was achieved in all cases. Minor adverse effects occurred in 13 patients (19%); they were headache (8), neck or back pain (3), vomiting (3), nausea (1), dizziness (1) and nystagmus (1) and were of minor degree in most and moderate in a few, lasting more than 24 hours in only one patient. EEG performed in 39 patients before and 24 h after the myelogram showed no seizure activity or significant change. Iohexol is a very satisfactory drug for all types of myelography.
报告了一项对68例成年患者使用含碘量300mg I/ml的碘海醇（欧乃派克）进行颈椎脊髓造影的开放性、非对照研究。所有病例均获得了满意的显影效果。13例患者（19%）出现了轻微不良反应；分别为头痛（8例）、颈部或背部疼痛（3例）、呕吐（3例）、恶心（1例）、头晕（1例）和眼球震颤（1例），大多数症状轻微，少数为中度，仅1例持续超过24小时。39例患者在脊髓造影前和造影后24小时进行的脑电图检查未显示癫痫活动或明显变化。碘海醇是用于各类脊髓造影的非常令人满意的药物。
