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正常受试者对急性冷暴露的循环儿茶酚胺、促甲状腺激素、甲状腺激素和催乳素反应。

Circulating catecholamine, thyrotrophin, thyroid hormone and prolactin responses of normal subjects to acute cold exposure.

作者信息

O'Malley B P, Cook N, Richardson A, Barnett D B, Rosenthal F D

出版信息

Clin Endocrinol (Oxf). 1984 Sep;21(3):285-91. doi: 10.1111/j.1365-2265.1984.tb03471.x.

DOI:10.1111/j.1365-2265.1984.tb03471.x
PMID:6478632
Abstract

The responses of circulating catecholamines, TSH, thyroid hormones and prolactin to 30 min of acute cold exposure (4 degrees C) were measured in eight normal volunteers over a 2 h period. There was a rise in circulating noradrenaline, TSH, T4 and T3 levels and a fall in circulating prolactin in the subjects studied, but no change in circulating adrenaline levels nor any alteration in the T4/T3 ratio. The thyroid axis of normal individuals can respond rapidly to acute cold exposure. In addition, the increased plasma noradrenaline levels accompanied by unaltered adrenaline levels suggest that the stimulus exerted by cold does not evoke a generalised stress response, but rather that the sympathetic nervous system is selectively stimulated.

摘要

在2小时内,对8名正常志愿者进行了测量,以观察其循环儿茶酚胺、促甲状腺激素(TSH)、甲状腺激素和催乳素在30分钟急性冷暴露(4摄氏度)后的反应。在所研究的受试者中,循环去甲肾上腺素、TSH、T4和T3水平升高,循环催乳素水平下降,但循环肾上腺素水平无变化,T4/T3比值也无改变。正常个体的甲状腺轴可对急性冷暴露迅速做出反应。此外,血浆去甲肾上腺素水平升高而肾上腺素水平未改变,这表明寒冷施加的刺激并未引发全身性应激反应,而是交感神经系统受到了选择性刺激。

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