Todokoro K, Kioussis D, Weissmann C
EMBO J. 1984 Aug;3(8):1809-12. doi: 10.1002/j.1460-2075.1984.tb02050.x.
A hitherto undescribed human interferon-alpha (IFN-alpha) gene, IFN-alpha 13, has been isolated and characterized. Its entire coding sequence is completely identical with that of IFN-alpha 1; the 5' and 3' non-coding regions differ by 4.5% and 3.8%, respectively. As the two genes are not allelic, we conclude that the similarity is due to a very recent gene conversion event. Both genes are expressed in virus-induced leukocytes.
一种此前未被描述的人类α干扰素（IFN-α）基因，即IFN-α 13，已被分离并进行了特征分析。其完整编码序列与IFN-α 1完全相同；5'和3'非编码区分别相差4.5%和3.8%。由于这两个基因不是等位基因，我们得出结论，这种相似性是由于最近发生的一次基因转换事件所致。这两个基因在病毒诱导的白细胞中均有表达。
