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肺部炎症的消退

Resolution of pulmonary inflammation.

作者信息

Henson P M, Larsen G L, Henson J E, Newman S L, Musson R A, Leslie C C

出版信息

Fed Proc. 1984 Oct;43(13):2799-806.

PMID:6479353
Abstract

Mononuclear phagocytes are suggested to play a major orchestrating role in the resolution of inflammatory processes in the lung. Particular emphasis is placed on their participation in the progression from a lesion with neutrophils as the dominant infiltrating cell to one that contains macrophages, on the macrophage's role in removing neutrophils and cell debris, and on their promotion of repair mechanisms. It is suggested that monocytes must mature into macrophages before they are capable of active participation in the resolution of inflammation.

摘要

单核吞噬细胞被认为在肺部炎症过程的消退中起主要协调作用。特别强调它们参与从以中性粒细胞作为主要浸润细胞的病变发展到含有巨噬细胞的病变过程,巨噬细胞在清除中性粒细胞和细胞碎片中的作用,以及它们对修复机制的促进作用。有人提出,单核细胞在能够积极参与炎症消退之前必须成熟为巨噬细胞。

相似文献

1
Resolution of pulmonary inflammation.肺部炎症的消退
Fed Proc. 1984 Oct;43(13):2799-806.
2
Complement fragments, alveolar macrophages, and alveolitis.补体片段、肺泡巨噬细胞与肺泡炎
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Resolution of inflammation. A perspective.炎症的消退:一种观点
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Alveolar macrophage replication. One mechanism for the expansion of the mononuclear phagocyte population in the chronically inflamed lung.肺泡巨噬细胞复制。这是慢性炎症肺部单核吞噬细胞群体扩张的一种机制。
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Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages.人单核细胞衍生巨噬细胞和兔炎性巨噬细胞对衰老中性粒细胞的吞噬作用。
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[Characteristics of mononuclear phagocytes in their normal state and in inflammation].[正常状态及炎症状态下单核吞噬细胞的特征]
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