Hatle L
Herz. 1984 Aug;9(4):213-21.
Noninvasive assessment of valvular lesions with Doppler echocardiography is based on determination of velocities of blood flow in the region of cardiac valves, adjacent cardiac chambers and in the large vessels. Obstructions lead to an increase in the velocity of flow in the region of the stenosis which can be registered with the Doppler technique. Through application of the Bernoulli equation, from the maximal velocity, the pressure gradient across the stenotic valve can be calculated. Additionally, the severity of the stenosis is reflected in the temporal course of the velocity curve of the jet through the stenosed valve. For this purpose, in mitral stenosis, the pressure half-time is employed and, in aortic stenosis, the peak of the velocity curve during systole is used. The severity of tricuspid and pulmonic stenosis can also be classified with a method analogous to that used in obstruction of the left heart. The diagnosis of valvular incompetence is based on the detection of regurgitant flow. The extent of regurgitant flow into the proximal cardiac chamber enables semiquantitative classification of severity. The intensity of the jet through the incompetent valve is also indicative of the size of the regurgitant volume. Similar to that in obstructive lesions, the temporal course of the velocity curve is also related to the severity. In association with high-grade regurgitant lesions, there is a premature decrease in the velocity curve. Additionally, the severity of aortic regurgitation can be assessed on the basis of the extent of regurgitant flow in the descending aorta or the subclavian arteries.(ABSTRACT TRUNCATED AT 250 WORDS)
利用多普勒超声心动图对瓣膜病变进行无创评估,是基于对心脏瓣膜区域、相邻心腔及大血管内血流速度的测定。梗阻会导致狭窄区域血流速度增加,这可用多普勒技术记录下来。通过应用伯努利方程,根据最大流速可计算出跨狭窄瓣膜的压力阶差。此外,狭窄的严重程度还反映在通过狭窄瓣膜的血流速度曲线的时间进程中。为此,在二尖瓣狭窄中采用压力减半时间,在主动脉瓣狭窄中则使用收缩期流速曲线的峰值。三尖瓣和肺动脉瓣狭窄的严重程度也可用类似于评估左心梗阻的方法进行分级。瓣膜关闭不全的诊断基于对反流的检测。反流至近端心腔的程度可对严重程度进行半定量分级。通过功能不全瓣膜的血流喷射强度也可指示反流容积的大小。与梗阻性病变类似,流速曲线的时间进程也与严重程度相关。在重度反流病变中,流速曲线会过早下降。此外,主动脉瓣反流的严重程度可根据降主动脉或锁骨下动脉的反流程度进行评估。(摘要截选至250词)