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亚甲基二苯胺引起的职业性肝炎。

Occupational hepatitis caused by methylenedianiline.

作者信息

Bastian P G

出版信息

Med J Aust. 1984 Oct 13;141(8):533-5. doi: 10.5694/j.1326-5377.1984.tb132915.x.

DOI:10.5694/j.1326-5377.1984.tb132915.x
PMID:6482804
Abstract

Four of the six workmen who were engaged in laying an epoxy resin based floor developed an acute hepatic illness; in two of these men, the illness recurred on re-exposure a few months later, and their convalescence period was prolonged. It was concluded that methylenedianiline, which was used as the curing agent for the epoxy resin, was the likely hepatotoxin on the basis of marked similarities of these men's symptoms and signs to those described in other published reports about toxic exposure to this compound. To date, there is no evidence of long-term liver damage caused by this widely used industrial chemical.

摘要

参与铺设环氧树脂地面的六名工人中有四人患上了急性肝病;其中两名工人在几个月后再次接触时病情复发,康复期延长。根据这些工人的症状和体征与其他已发表的关于该化合物毒性暴露报告中所描述的显著相似性,得出结论:用作环氧树脂固化剂的亚甲基二苯胺可能是肝毒素。迄今为止,尚无证据表明这种广泛使用的工业化学品会造成长期肝损伤。

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