Fonseca V, Tongia R, el-Hazmi M, Abu-Aisha H
Postgrad Med J. 1984 Sep;60(707):589-91. doi: 10.1136/pgmj.60.707.589.
Plasma 25-hydroxy cholecalciferol (25-OH vitamin D) concentrations were measured in 31 adult Saudi Arabian women who presented with acute minor illness. Patients with chronic diseases, malignancy and overt metabolic bone disease were excluded from this study. The median plasma 25-OH vitamin D concentration was 6 ng/ml (range: 2-18 ng/ml). Only three subjects had a concentration within the normal range (10-55 ng/ml). Plasma 25-OH vitamin D concentrations were significantly lower in subjects living in apartments than in those living in villas or rural areas (P less than 0.02). When direct questioning was used to assess exposure to sunlight, plasma 25-OH vitamin D concentrations were significantly lower in those subjects whose average exposure was less than 30 min daily than those whose exposure was more than 30 min daily (P = 0.002). Our findings confirm the importance of inadequate exposure to sunlight in the aetiology of vitamin D deficiency. Social customs may contribute to this deficiency in spite of abundant sunshine. Direct questioning to assess the adequacy of sunlight exposure is an essential part of history taking in cases of suspected vitamin D deficiency.
对31名患有急性轻症疾病的沙特成年女性测量了血浆25-羟基胆钙化醇(25-OH维生素D)浓度。患有慢性疾病、恶性肿瘤和明显代谢性骨病的患者被排除在本研究之外。血浆25-OH维生素D浓度中位数为6 ng/ml(范围:2 - 18 ng/ml)。只有三名受试者的浓度在正常范围内(10 - 55 ng/ml)。居住在公寓中的受试者血浆25-OH维生素D浓度显著低于居住在别墅或农村地区的受试者(P < 0.02)。当使用直接询问法评估阳光照射情况时,平均每日阳光照射少于30分钟的受试者血浆25-OH维生素D浓度显著低于每日照射超过30分钟的受试者(P = 0.002)。我们的研究结果证实了阳光照射不足在维生素D缺乏病因学中的重要性。尽管阳光充足,但社会习俗可能导致了这种缺乏。在疑似维生素D缺乏的病例中,通过直接询问来评估阳光照射是否充足是病史采集的重要组成部分。